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Sodium thiosulfate interacts directly with cisplatin to produce an inactive platinum species. In addition, sodium thiosulfate can enter cells through the sodium sulfate cotransporter 2 and cause intracellular effects such as the increase in antioxidant glutathione levels and inhibition of intracellular oxidative stress.
Nitric acid and Sodium Thiosulfate Reaction | HNO3
Hot concentrated nitric acid and sodium thiosulfate. With dilute nitric acid, sodium sulfate (Na 2 SO 4), nitrogen dioxide (NO 2), sulfur (S) and water (H 2 O) can be given as products.. 2HNO 3 + Na 2 S 2 O 3 → 2NO 2 + S + Na 2 SO 4 + H 2 O. Yellow/white colour precipitation (sulfur) can be observed in this occasion too.
Treatment of calcinosis cutis with sodium thiosulfate therapy
Treatment of calcinosis cutis with sodium thiosulfate therapy. Treatment of calcinosis cutis with sodium thiosulfate therapy. J Am Acad Dermatol. 2020 Nov;83 (5):1518-1520. doi: 10.1016/j.jaad.2020.06.996. Epub 2020 Jul 2.
Sodium Thiosulfate Pentahydrate | ACS Reagent Chemicals
This monograph for Sodium Thiosulfate Pentahydrate provides, in addition to common physical constants, a general description including typical appearance, applications, change in state (approximate), and aqueous solubility. ... Assay, pH of a 5% Solution at 25.0 °C, Insoluble Matter, Nitrogen Compounds, Sulfate, Sulfite, and Sulfide. …
Sodium Thiosulfate | Na2S2O3 | CID 24477
CID 24478 (Thiosulfuric acid) Sodium thiosulfate is an inorganic sodium salt composed of sodium and thiosulfate ions in a 2:1 ratio. It has a role as an antidote to cyanide poisoning, a nephroprotective agent and an …
SAFETY DATA SHEET Revision Date 05/25/2023 Version …
Product name : Sodium thiosulfate Product Number : 217263 Brand : SIGALD CAS-No. : 1.2 Relevant identified uses of the substance or mixture and uses advised against ... Synonyms : Sodium thiosulphate . SIGALD - 217263 Page 2 of 10 The life science business of Merck KGaA, Darmstadt, Germany operates as MilliporeSigma in …
USP Monographs: Sodium Thiosulfate
USP Monographs: Sodium Thiosulfate. Sodium Thiosulfate. Na 2 S 2 O 3 ·5H 2 O 248.19. Thiosulfuric acid, disodium salt, pentahydrate. Disodium thiosulfate pentahydrate. [ 1 ]. Anhydrous. 158.11 [ ]. » Sodium Thiosulfate contains not less than 99.0 percent and not more than 100.5 percent of Na 2 S 2 O 3, calculated on the ...
Sodium Thiosulfate: Dosage, Mechanism/Onset of …
Sodium Thiosulfate. Generic name: sodium thiosulfate systemic. Brand names: Pedmark. Reviewed by Medicine on February 17, 2020. Dosage Forms. …
Sodium Thiosulfate | Formula, Properties & Application
The chemical formula of Sodium Thiosulfate is Na 2 S 2 O 3. It commonly appears as a white crystalline or powder form, though it is also available as a pentahydrate (Na 2 S 2 O 3 ·5H 2 O). As a salt of a weak base (sulfurous acid) and a weak acid (thiosulfuric acid), it is a stable compound under normal conditions but may decompose under heat ...
The oxidation of thiosulfates with copper sulfate. Application …
All the reagents used in this study (sodium thiosulfate, copper sulfate 6-hydrate, calcium oxide, magnesium oxide, sodium hydroxide and sulfuric acid) were of laboratory grade. 2.1. Experimental procedure for thiosulfate transformation at high temperature and pressure
Sodium Thiosulfate: Indications, Side Effects, …
Use sodium thiosulfate as ordered by your doctor. Read all information given to you. Follow all instructions closely. 1. It is given as an infusion into a vein over a … See more
The chemistry of thiosulfate and vascular calcification
Sodium sulfate (Na 2 SO 4) inhibited aortic calcification at similar concentrations, indicating that the effect is not specific for thiosulfate. NaCl at the same ionic strength produced much less inhibition, indicating that an increase in ionic strength was not the sole explanation.
Anaerobic thiosulfate oxidation by the
Furthermore, we show that Roseobacter strains can grow and oxidize thiosulfate to sulfate under both aerobic and anaerobic conditions. ... (pH 8.0), 200 µM of sodium hydrogen phosphate, ...
Science made alive: Chemistry/Riddles
Dissolve some copper sulfate in one test tube and some sodium thiosulfate in another test tube. For the thiosulfate an excess amount should be used. A good guideline is to use one spatula full of copper sulfate and four of the same spatulas full of sodium thiosulfate. These two solutions are shown in the left picture.
Sodium thiosulfate anhydrous, ≥99% | Sigma-Aldrich
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others. Contact Technical Service. Sodium thiosulfate anhydrous, ≥99%; CAS Number: ; EC Number: 231-867-5; Linear Formula: Na2S2O3; find Sigma-Aldrich-S1648 MSDS, …
The effect of sodium thiosulfate dechlorination on fecal indicator
Two samples (one with sodium thiosulfate and one without sodium thiosulfate) were collected from sources including water treatment plants, storage tanks, and distribution network taps. Samples were placed on ice and assayed for thermotolerant coliforms within 8 hours using membrane filtration with m-lauryl sulfate media.
A novel bacterial thiosulfate oxidation pathway provides …
For the measurement of thiosulfate, sulfate, ZVS and tetrathionate, wild type E. flavus 21–3 and corresponding mutants were grown at 28 °C in ASW 2216E supplemented with 40 mM thiosulfate.
Catalysis of a sodium thiosulfate and iron(III) …
Iron(II) sulfate, FeSO 4 (aq) – see CLEAPSS Hazcard HC055B and Recipe Book RB051. ... Sodium thiosulfate solution, Na 2 S 2 O 3 (aq) – see CLEAPSS Hazcard HC095A and Recipe Book RB087. It is important …
Sodium Thiosulfate in the Treatment of Calciphylaxis
Sodium thiosulfate (STS) is a powerful antioxidant and chelating agent, which has been traditionally used for cyanide poisoning and cisplatin toxicity. There are increasing …
Sodium Thiosulfate: Uses, Warnings, Side Effects, …
Sodium thiosulfate is a medication used as an antidote to cyanide poisoning. Common side effects of sodium thiosulfate include nausea, vomiting, …
Sodium Thiosulfate: Uses, Warnings, Side Effects, Dosage
Sodium thiosulfate is a medication used as an antidote to cyanide poisoning. Common side effects of sodium thiosulfate include nausea, vomiting, headache, low blood pressure (hypotension), salty taste in the mouth, warm sensation over the body, prolonged bleeding time, hypersensitivity reactions, local irritation, and contact dermatitis. Consult …
Sodium Thiosulfate (Intravenous Route) Description …
Sodium thiosulfate may be used to lessen some of the side effects of cisplatin (a cancer medicine). It is also used with another medicine in the emergency …
Crystal structure of sodium thiosulfate dihydrate and …
The sodium cations are five- to seven-coordinate by thiosulfate anions and water molecules and the anions act as mono- and bidentate ligands. In the extended structure, the thiosulfate anions and water molecules are connected by O—H⋯O and O—H⋯S hydrogen bonds of medium strength to form corrugated layers, which are linked …
Sodium thiosulfate Advanced Patient Information
High blood pressure (hypertension) or. Kidney disease or. Liver disease or. Toxemia of pregnancy—Sodium thiosulfate may cause the body to retain (keep) water, which may make these conditions worse. Kidney disease—Use with caution. The effects may be increased because of the slower removal of the medicine from the body.
Sodium Thiosulphate
Sodium thiosulphate has a chemical formula of Na 2 S 2 O 3 and a molar mass of about 158.11 g/mol. The substance well exists in the form of pentahydrate salts (Na 2 S 2 O 3 .5H 2 O), having a molar mass measuring about 248.18 g/mol. Sodium thiosulphate is an ionic compound which consists of two cations of sodium atom (Na+) and a negatively ...
H2S in Critical Illness—A New Horizon for Sodium Thiosulfate?
Thiosulfate is further oxidized into sulfate. In turn, in particular under hypoxic and reducing conditions, H 2 S can be regenerated from exogenously administered thiosulfate by rhondanese and, ... Sodium thiosulfate (Na 2 S 2 O 3) is a clinically approved H 2 S donor with a good safety profile.
Sodium Thiosulfate (Na2S2O3) [Hypo Solution …
Sodium thiosulfate, commonly known as sodium thiosulphate, is a medicine that is used to treat cyanide poisoning, pityriasis versicolor, and cisplatin side effects. It is …
How Sodium Thiosulfate Neutralizes Chlorine: Mechanism, …
Sodium sulfate is a compound composed of sodium, sulfur, and oxygen atoms. This compound is not directly involved in neutralizing chlorine but is rather a byproduct of the reaction. The release of sodium sulfate signifies the completion of the between sodium thiosulfate and chlorine, indicating that the chlorine has been …
Hydrogen Sulfide Metabolite, Sodium Thiosulfate: …
Thiosulfate in the form of sodium thiosulfate (STS) is a major oxidation product of hydrogen sulfide (H 2 S), an endogenous signaling molecule and the …
Sodium Thiosulfate | Encyclopedia
Sodium ThiosulfateOVERVIEWSodium thiosulfate (SO-dee-um THYE-oh-SUL-fate) is a colorless to white crystalline solid or powder with no odor and a cooling, bitter taste. The compound usually occurs in the form of the pentahydrate (Na2S2O3·5H2O). Sodium thiosulfate is an antichlor, a compound that reacts with and neutralizes excess chlorine …