thallium poisoning chronic

Long‐term misdiagnosis and neurologic outcomes of …

The long‐term prognosis of thallium poisoning depends on the total dose ingested, the timing of treatment, and the individual susceptibility of each patient (Huang et al., 2014). Most of the symptoms of thallium poisoning can be completely reversed, but …

Thallium: a review of public health and environmental …

With a mining history of 350 years, the Lanmuchang Hg–Tl deposit has caused many people to suffer from chronic thallium poisoning with a scale and severeness that no parallel is ever known in the world. Major symptoms of thallium poisoning include anorexia, headache, pains in abdomen, upper arms and thighs and …

Emerging Thallium Pollution in China and Source Tracing by Thallium …

Thallium (Tl) is one of the most toxic trace metals on Earth and can cause both chronic and acute poisoning. Tl is listed by both the United States Environmental Protection Agency (EPA) and the European Union (EU) as a dangerous pollutant. Tl is also considered a priority pollutant in both the 12th and 13th five-year plans in China.

Thallium Toxicity: Practice Essentials, Background, …

Acute thallium poisoning is primarily characterized by gastrointestinal, neurologic, and dermatologic symptoms, while neurologic findings predominate with chronic exposure and tend to progress, even despite decreasing blood thallium levels. ... Because chronic thallium exposure mimics other diseases, cases of industrial thallium …

Thallium poisoning: a review

Thallium poisoning is one of the most complex and serious toxicities known to man. The symptomatology of its toxicity is usually nonspecific due to the multi-organ involvement. The initial symptoms of thallium poisoning may include fever, gastrointestinal problems, delirium, convulsions and coma. Symptoms may appear rapidly, but more commonly ...

Cardiopulmonary Effects of Acute Thallium Poisoning

Alopecia is considered the hallmark of chronic thallium intoxication. Descriptions of myocardial disease are usually limited to electrocardiographic abnormalities and sinus tachycardia. ... Her symptoms and association with patient 3 raised suspicion for thallium poisoning, which was confirmed by a serum thallium level of 422μg/100 ml and a ...

Chronic thallium poisoning | Health & Environmental …

5473864. Abstract. IPA COPYRIGHT: ASHP A case of chronic thallium poisoning in a male is presented. During a total course of at least 5 years the characteristic symptoms of loss of hair and pains in the limbs were late to appear, thereby causing a delay in the diagnosis. The patient's denial of a possible contact with thallium was another ...

Diagnosis and treatment of persons with acute thallium poisoning

Methods. Forty-four persons (12 males and 32 females) with acute oral thallium poisoning were tested for thallium levels in blood and urine and examined by a toxicologist and a neurologist, and in some –cases, by a gynecologist, an ophthalmologist, and a psychiatrist. Persons were divided into the following three groups depending on …

Clinical characteristics and treatment of thallium poisoning in

Patients with chronic thallium poisoning and patients with other poisoning were excluded. To distinguish the clinical features of patients with different admission times and according to the stages of thallium poisoning, we divided patients into 3 groups according to the time from symptom onset to admission. Patients admitted to the hospital ...

Thallium Induced Sub-chronic Toxicity Profile in Wistar Rats

Keywords: Repeated 90 days study, Sub-chronic toxicity, Thallium sulfate (I), Wistar rats Ind J Vet Sci and Biotech (2022): 10.48165/ijvsbt.18.5.19 Thallium Induced Sub-chronic T oxicity Profile ...

Thallium | SpringerLink

Thallium salts dissolve readily in water and are odorless and tasteless. Download reference work entry PDF. Thallium (Tl) was first discovered by Sir William Crooks in 1861, with its toxicity recognized shortly afterwards [ 1, 2 ]. The element is classified in group IIIA of the periodic table and forms both monovalent and trivalent …

Thallium Toxicity Clinical Presentation

The clinical presentation of thallium toxicity can vary depending on the type, severity, and timeframe of the exposure. Acute thallium poisoning is primarily characterized by gastrointestinal, neurological, and dermatological symptoms, while neurologic findings predominate with chronic exposure and tend to progress, even …

News | California Poison Control System

Call the Poison Hotline. Call toll-free 24-hours a day, 365 days a year, with poison-related questions or for help. 1‑800‑222‑1222. Order Print Materials. Order free educational materials like stickers, magnets, and brochures to distribute to large audiences. We ship anywhere in California for free. Order Materials.

Thallium: What Are the Symptoms of Poisoning?

Get the facts about thallium poisoning side effects, health risks and toxicity testing. Learn the metal's characteristic, uses and where it is naturally found. ... Neuropathic pain is a chronic condition that leads to ongoing pain symptoms. Patients can be predisposed to developing neuropathic pain who have conditions such as diabetes, cancer ...

Thallium Toxicity | Treatment & Management | Point of Care

Introduction. Thallium, a chemical element with the symbol TI, has an atomic number 81 on the periodic table. Thallium sulfate was once used as an ant and rat …

VisualDx

Thallium poisoning may be acute, subacute, or chronic in nature. The acute form, which is most common, develops rapidly and is the result of short exposures to high doses. The timeline of symptoms following thallium poisoning is as follows: Gastrointestinal / renal – Symptoms develop within 1-5 days of ingestion and include …

Thallium toxicity

Evaluation. Urine thallium concentration >20mcg/L indicates toxicity. Blood levels are not considered reliable except in large exposures. Plain films may be useful in acute ingestion because thallium is radiopaque.

Thallium pollution in China: A geo-environmental perspective

The enrichments of Tl in local soil, water, and crops may result in Tl pollution and consequent adverse health effects, e.g. chronic Tl poisoning. Investigation of the baseline Tl in the geo-environment, proper land use and health-related environmental planning and regulation are critical to prevent the Tl pollution.

Thallium Poisoning

In chronic poisoning, the most striking feature is the loss of hair. This phenomenon, so characteristic of thallium poisoning, is probably the result of cessation of cell proliferation in the hair follicles (Cavanagh and Gregson, 1978) and thus closely resembles the hair loss caused by X-irradiation and radiomimetic chemicals.

Thallium poisoning | DermNet

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Do you have thallium poisoning?

WEBAcute thallium poisoning is primarily characterized by gastrointestinal, neurologic, and dermatologic symptoms, while neurologic findings predominate …

Thallium Poisoning

Chronic thallium poisoning primarily damages the extrapyramidal system, which choreic and athetotic movements often characterized (Prick, 1979). Along with this, indigestion, movement disorders, endocrine disruptions, lack of resistance to infection, lack of appetite, weight loss, brain and nervous disorders with intellectual disabilities, and ...

Thallium | Public Health Statement | ATSDR

It has been estimated that the average person eats, on a daily basis, 2 parts thallium per billion parts (ppb) of food. Even though rat poison containing thallium was banned in 1972, accidental poisonings from old rat poison still occur, especially in children. Thallium is produced or used in power plants, cement factories, and smelters.

Thallium: Systemic Agent | NIOSH | CDC

It is unknown whether chronic or repeated exposure to thallium increases the risk of reproductive toxicity or developmental toxicity. Chronic high level exposure to thallium through inhalation has been reported to cause nervous system effects, such as numbness of fingers and toes. Thallium may cross the placental barrier in humans and may be ...

Chronic thallium poisoning: Rapid diagnosis and treatment

A rapid method for laboratory diagnosis and a rational form of therapy for thallium poisoning is presented. CASE REPORT A 3-year-old, white male was admitted to the St. Louis Children's Hospital on March I8, 1961, with a history of ingestion of an undeter- mined amount of thallium-coated peanuts 1 month prior to admission.

Long‐term misdiagnosis and neurologic outcomes …

1 INTRODUCTION. Thallium is one of the most toxic heavy metals and is widely used in the manufacturing of highly regulated products (Baldwin, 1999).The hallmark symptoms of thallium poisoning are digestive …

Thallium poisoning: a case report

Thallium poisoning is usually accidental. We present a case of a 51-year-old woman who was evaluated in June 2018 for myalgia, vertigo, asthenia, and abdominal pain. ... After making the diagnosis of chronic thallium intoxication, chelation therapy was started with oral D-penicillamine 250 mg every 6 hours. The patient presented a …

HEALTH EFFECTS

No studies were located regarding neurological effects in humans after intermediate oral exposure to thallium. Peripheral neuropathy was reported in 189 cases of thallium poisoning in China from 1960 to 1977 (Dai-xing and Ding-nan 1985). Thallium was detected in urine samples of the exposed group at higher levels (0.6-2.25 mg/L, P>0.01) …