Mylan Sotradecol
Mylan Sotradecol. Sotradecol ® has been used by healthcare providers since FDA-approval in 1946. Sotradecol is: The only commercially available sodium tertradecyl sulfate injection in the U.S. Market. Available in two concentrations – 1% (10 mg/mL) and 3% (30 mg/mL) Accessible through Mylan's distributor, FFF Enterprises.
Tetradecyl hydrogen sulfate (ester)
Indication. Sotradecol (sodium tetradecyl sulfate injection) is indicated in the treatment of small, uncomplicated varicose veins of the legs showing simple dilation, with competent valves 1. Sodium tetradecyl sulfate has been designated as an orphan drug by the FDA for the treatment of gastrointestinal bleeding due to esophageal varices 8.
DailyMed
In the rat, the acute intravenous LD 50 of sodium tetradecyl sulfate was estimated to be between 72 mg/kg and 108 mg/kg. Purified sodium tetradecyl sulfate was found to have an LD 50 of 2 g/kg when administered orally by stomach tube as a 25% aqueous solution to rats. In rats given 0.15 g/kg in drinking water for 30 days, no …
Sodium Tetradecyl Sulfate: Varicose Vein Uses, Side Effects
Sodium tetradecyl sulfate is a medication used to treat small uncomplicated varicose veins in the lower limbs. Varicose veins are superficial, twisted, enlarged veins …
Sodium Tetradecyl Sulfate: Side Effects, Uses, Dosage
Dosages of Sodium Tetradecyl Sulfate: Dosage Forms and Strengths. Injectable Solution. 1%. 3%. Dosage Considerations – Should be Given as Follows: Venous Varices. May administer a test dose of 0.5 mL several hours before treating with larger doses. 0.5-2 mL intravenously (IV) (preferably 1 mL) in each vein; 1% solution for general use and 3% ...
Sodium Tetradecyl Sulfate
Sodium tetradecyl sulfate is an anionic surfactant which occurs as a white, waxy solid. The structural formula is as follows: C 14 H 29 NaSO 4 7-Ethyl-2-methyl-4-hendecanol sulfate sodium salt MW 316.44. Sodium tetradecyl sulfate injection is a sterile nonpyrogenic solution for intravenous use as a sclerosing agent.
Sodium Tetradecyl Sulfate (Intravenous Route)
Descriptions. Sodium tetradecyl sulfate injection is used to treat small varicose veins of the lower legs. It is a type of medicine called a sclerosing agent. This medicine is to be given only by or under the direct supervision of your doctor. This product is available in the following dosage forms: Solution.
Sodium Tetradecyl Sulfate
8600 Rockville Pike. HHS Vulnerability Disclosure. No information is available on the clinical use of sodium tetradecyl sulfate during breastfeeding. Although sodium tetradecyl sulfate is unlikely to adversely affect the breastfed infant, international guidelines recommend that breastfeeding be withheld for 2 days after sclerotherapy. [1]
Fibrovein 3% Solution for Injection
Fibrovein containing sodium tetradecyl sulfate is administered directly into the lumen of the isolated segment of vein/venule. Distribution In humans, the majority (75 %) of an injected dose of radiolabelled 3 % sodium tetradecyl sulfate rapidly disappeared from the empty varicose vein injection site into communicating blood vessels with rapid ...
Sodium Tetradecyl Sulfate
Last updated February 6, 2020. Includes Sodium Tetradecyl Sulfate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, …
European guidelines for sclerotherapy in chronic venous disorders
The guideline gives recommendations concerning indications, contraindications, side-effects, con … This guideline focuses on the two sclerosing drugs which are licensed in the majority of the European countries, polidocanol and sodium tetradecyl sulphate. Other sclerosants are not discussed in detail. The guideline gives recommendations ...
SOTRADECOL SODIUM TETRADECYL SULFATE injection, solution
Sodium tetradecyl sulfate is an anionic surfactant which occurs as a white, waxy solid. The structural formula is as follows: C14H29NaSO4 7-Ethyl-2-methyl-4-hendecanol sulfate sodium salt MW 316.44. Sotradecol (sodium tetradecyl sulfate injection) is a sterile nonpyrogenic solution for intravenous use as a sclerosing agent.
Sodium Tetradecyl Sulfate injection
SODIUM TETRADECYL SULFATE (SOE dee um tet ra DES uhl SUHL feyt) is used to improve the appearance of varicose veins. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. COMMON BRAND NAME (S): Sotradecol. Cleveland Clinic is a non-profit academic medical center.
Fibrovein
It is a sterile aqueous injection of Sodium Tetradecyl Sulfate (STS), an anionic detergent. It has been used in the treatment of varicose veins since 1946. Fibrovein is manufactured under cGMP conditions and complies with all EU regulations. The product was first registered in the UK in 1967 when it was marketed under the name of STD injection.
Sotradecol Uses, Side Effects & Warnings
pain, itching, peeling, skin sores, or skin changes where the medicine was injected. Common side effects of Sotradecol may include: mild headache; nausea, vomiting; or. discolored skin along the treated vein (may be permanent). This is not a complete list of side effects and others may occur. Call your doctor for medical advice …
Trombovar (Sodium Tetradecyl Sulfate) | RxMed: Diseases …
TROMBOVAR® Therapex Sodium Tetradecyl Sulfate Sclerosing Agent. Indications And Clinical Uses: Sclerosing treatment of varicose veins in the legs, using compression sclerotherapy. Contra-Indications: Incompetency of collateral deep veins in the legs; incompetency of the valves of the greater and lesser saphenous veins before ligation of …
Progress in Endoscopic Treatment of Hemorrhoids
Sodium tetradecyl sulfate, a drug approved by the FDA for the treatment of varicose veins of lower extremities, makes the submucosal tissue fibrotic, and then fixes the hemorrhoidal tissue. The common method of sclerotherapy is to inject 0.5–2.0 mL of 1% sodium tetradecyl sulfate or 5% phenol under the mucosa at the top of the …
Sotradecol (Sodium Tetradecyl): Side Effects, Uses, Dosage
Sotradecol® (sodium tetradecyl) (sodium tetradecyl sulfate injection) is indicated in the treatment of small uncomplicated varicose veins of the lower …
Injection sclerotherapy techniques for the treatment of
INTRODUCTION. Injection sclerotherapy is a minimally invasive percutaneous technique using chemical irritants to close unwanted superficial veins [].Sclerotherapy is primarily used in the treatment of telangiectasias, reticular veins, and small nonaxial varicose veins (<6 mm), which may or may not be symptomatic, and even …
Sodium Tetradecyl Sulfate
A Prospective Clinical Trial Evaluating the Efficacy of 1.5% Sodium Tetradecyl Sulfate Injection for the Treatment of Epidermoid Cysts The objective of this study is to determine the efficacy, safety, tolerability, and patient satisfaction associated with the treatment of epidermoid cysts with injected 1.5% sodium tetradecyl sulfate …
Sodium Tetradecyl Sulfate Injection, 3% 60 mg/2 mL (30 …
Sodium tetradecyl sulfate injection is for intravenous use only. The strength of solution required depends on the size and degree of varicosity. In general, the 1% solution will be found most useful with the 3% solution preferred for larger varicosities. The dosage should be kept small, using 0.5 mL to 2 mL (preferably 1 mL maximum) for each ...
Sodium Tetradecyl Sulfate Dosage Guide
Sodium tetradecyl sulfate should only be administered by a physician familiar with the diagnosis and treatment of conditions affecting the venous system and with the proper injection technique. Extravasation may result in severe local adverse reactions including necrosis. Extreme care in needle placement and use of the minimal effective …
Sodium Tetradecyl Sulfate (Local) (Monograph)
Generally use 1% solution; 3% solution preferred for larger varicosities. 5–20 mg of the 1% sodium tetradecyl sulfate solution (0.5–2 mL, preferably ≤2) or 15–60 mg of the 3% sodium tetradecyl sulfate solution (0.5–2 mL, preferably ≤2) recommended by manufacturer for each injection site. Do not exceed 2 mL per injection site or 10 ...
Sotradecol (sodium tetradecyl sulfate) dose, indications, …
PDR Drug Summaries are concise point-of-care prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice PDR's drug summaries are available free of charge and serve as a great resource for US based MDs, DOs, NPs and PAs in patient practice
sodium tetradecyl sulfate
sodium tetradecyl sulfate sodium sotradecol sotradecol tetradecyl sulfuric acid ... indication: 128060009: DOID:799: Incompetence of any valvular structure: contraindication: 10337008: Infection of skin AND/OR subcutaneous tissue: contraindication: 19824006: Peripheral venous insufficiency:
Sodium tetradecyl sulfate: Uses, Interactions, Mechanism of …
Indication. For the treatment of small uncomplicated varicose veins of the lower extremities that show simple dilation with competent valves. Build, train, …
The Use of Sodium Tetradecyl Sulphate for the Treatment …
Each milliliter of 3 % STS contains 30 mg of sodium tetradecyl sulfate, 0.02 ml of benzyl alcohol, and 9.0 mg of dibasic sodium phosphate, anhydrous in water for injection at a pH of 7.9; monobasic sodium phosphate and/or sodium hydroxide were added, if needed for pH adjustment . All the patients received an oral analgesic and a …
Sotradecol: Package Insert
polidocanol, Varithena, sodium tetradecyl sulfate, Asclera Indications and Usage for Sotradecol. Sotradecol (sodium tetradecyl sulfate injection) is indicated in the treatment of small uncomplicated …
Sclerosing agents for use in GI endoscopy
Sodium tetradecyl sulfate is 7-ethyl-2-methyl-4-hendec-anol sodium sulfate (C14H29NaSO4). It is a synthetic an-ionic surfactant that is available as 1% and 3% aqueous solutions with 2% benzyl alcohol and is buffered to a pH of 7.9 with sodium phosphate.1,4It is packaged in 2-mL. TABLE 1. Sclerosants. Volume, mL.
Sodium tetradecyl sulfate
Sodium tetradecyl sulfate; Adult Indications & Dosage: Pediatric Indications & Dosage: Contraindications: Warnings & Precautions: Adverse Reactions: Drug Interactions: ... Sodium tetradecyl sulfate is a sclerosing Agent that is FDA approved for the treatment of small uncomplicated varicose veins of the lower extremities.