The association between serum copper
In model 2, after adjusting for gender, age, it was found that higher serum copper concentration was positively associated with diabetes, and the trend test was statistically significant (p for trend<0.05). Compared with Q1, the OR of the highest serum copper levels group (Q4) was 1.49 (95% CI: 1.11–2.01).
Serum Copper Concentrations, Effect Modifiers and Blood …
The serum copper concentration was quantified using inductively coupled plasma dynamic reaction cell mass spectrometry (ICP-DRC-MS), a powerful multielement analytical technique with the ability to detect even trace levels of elements. All the data exceeded the lower limit of detection (LLOD) for the tests. The LLOD of serum copper …
Serum copper-to-zinc ratio and risk of incident pneumonia …
Serum copper (Cu) and zinc (Zn), essential micronutrients that have important immunomodulatory and antimicrobial properties, are biomarkers of ageing. Serum Cu/Zn-ratio may be a more reliable marker for age-related degenerative conditions compared with serum Cu or Zn alone. We aimed to assess the association between Cu/Zn-ratio and the …
Serum copper levels are associated with bone mineral …
In epidemiological studies, serum copper levels in patients with osteoporosis, lumbar osteopenia and femoral neck fracture were lower than those in the normal group, and low serum copper levels were also considered as a risk factor for age-related osteoporosis. Some even suggested that copper could be used as a simple …
Association of Serum Concentrations of Copper, Selenium, …
Recently, Luo found that serum copper level was inversely linked with BMI-corrected handgrip strength, and the beta coefficients (95% confidence intervals) comparing the fourth to the lowest quartiles of serum Cu concentration was − 0.36 kg (− 0.44; − 0.28); and a non-linear association was detected between them, also in line with our ...
Maternal Serum Zinc, Copper, Magnesium, and Iron in …
Serum iron was measured by ferrozine method, magnesium by magnesium-calmagite method, zinc was measured using zinc reaction with nitro-PAPS and copper reaction with Di-Br-PAESA using the spectrophotometer. [10, 11] Samples were treated with 1% fresh hypochlorite solution for 30 min before they were discarded. Means were used …
Association between serum copper levels and stroke …
Volume 33, Issue 1, January 2024, 107473. Association between serum copper levels and stroke in the general population: A nationally representative study. Author links open …
Nutrition Information Brief—Copper
Moderate to severe copper deficiency is typified by decrements in serum copper and CP activity ( 6 ). CP carries most circulating copper; thus, changes in blood copper likely reflect changes in CP concentrations. Using serum Cu and CP activity as bioindicators of copper status is, however, complicated because infection and …
Relationship of serum copper and zinc with kidney …
Article. Published: 29 July 2022. Nutrition in acute and chronic diseases. Relationship of serum copper and zinc with kidney function and urinary albumin to creatinine ratio: …
Wilson Disease
Staging of Wilson Disease. Stage 1: initial accumulation of copper in the liver. Stage 2: Acute redistribution of copper within the liver, followed by release into the systemic circulation. Stage 3: Chronic accumulation of copper into extrahepatic tissues including brain. Stage 4: Use of chelation therapy to restore copper balance.
Copper: Reference Range, Interpretation, Collection …
Serum ceruloplasmin is also a valuable test and can be used to determine the free serum copper. Copper reference ranges are as follows: Free serum copper: 1.6-2.4 μmol/L or …
Frontiers | High Serum Copper as A Risk Factor of All-Cause …
Background: Several studies have shown that serum copper levels are related to coronary heart disease, diabetes, and cancer. However, the association of serum copper levels with all-cause, causespecific (including cardiovascular disease [CVD] and cancer) mortality remains unclear.Objectives: This study aimed to prospectively examine …
Serum copper levels and risk of major adverse …
The aims of this study were to investigate the association between S-Cu and risk of major adverse cardiovascular events (MACE), including total stroke, ischemic stroke, hemorrhagic stroke, myocardial infarction and cardiovascular …
The Association Between Serum Levels of Selenium, Copper …
There are conflicting reports on the correlation between serum levels of selenium (Se), copper (Cu), and magnesium (Mg) with thyroid cancer. The purpose of the present study is to clarify the association between Se, Cu, and Mg levels with thyroid cancer using a meta-analysis approach. We searched articles indexed in PubMed published as …
Isotopic composition of serum zinc and copper in healthy …
No significant difference in isotopic composition of serum zinc or copper with respect to healthy controls and ASD children were identified. However, the isotopic composition of serum copper in boys was found to be enriched in 65 Cu in comparison to previously published healthy adult copper isotopic composition. Furthermore, in both …
Serum copper to zinc ratio: Relationship with aging …
Serum copper to zinc ratio: Relationship with aging and health status - ScienceDirect. Mechanisms of Ageing and Development. Volume 151, November 2015, …
Association of serum copper (Cu) with
Background Copper (Cu) homeostasis and Cu-induced cell death are gaining recognition as crucial processes in the pathogenesis of cardiovascular disease (CVD). Circulating Cu associated with CVD and mortality is yet to be fully elucidated. Objective This national prospective cohort study is to estimate relationship between serum Cu and the …
Association Between the Change of Serum Copper and …
This article was performed through using Preferred Reporting Items about Systematic Reviews and Meta-Analyses guidelines to select relevant studies between serum copper and ischemic stroke (Beller et al. 2013). Search terms were the following: "trace elements" or "copper" or "Cu" and "cerebrovascular disease" or "stroke" or ...
Association between serum copper levels and stroke in the …
When serum copper was estimated as a categorical variable, subjects with levels in the highest tertile (T3, >19.8 µmol/l), but not the middle tertile (T2, 16.4-19.8 µmol/l), had an increased prevalence of stroke compared to those with levels in the lowest tertile (T1, <16.4 µmol/l) in crude logistic regression (T3: ...
The association between serum copper
ORIGINAL ARTICLE. Open Access. The association between serum copper concentration and prevalence of diabetes among US adults with hypertension (NHANES …
Total Copper (Blood) | University Hospitals
Ask your healthcare provider what your test results mean for you. The normal range for total copper in the blood is 62 to 140 micrograms per deciliter (mcg/dL). A low amount of copper could mean that you have: Kidney disease. A nutritional deficiency. Inability …
Serum copper levels are associated with bone mineral density …
As shown in Table 1 and Figure 1, 722 subjects aged 18-years or older were included in this study.For exposures of interest, serum copper concentrations (108 vs. 130 μg/dL) were significantly lower in men than in women. For outcomes of interest, BMD in total femur (1.00 vs. 0.91 g/cm 2), femoral neck (0.81 vs. 0.76 g/cm 2) and total spine …
Serum Copper-to-Zinc Ratio and Risk of Chronic Obstructive …
Purpose Serum copper (Cu), zinc (Zn), and Cu/Zn-ratio have emerged as ageing-related biomarkers. We sought to assess the association between Cu/Zn-ratio and chronic obstructive pulmonary disease (COPD) risk. Methods Serum Cu and Zn were measured using atomic absorption spectrometry in 2,503 men aged 42–61 years. …
Serum Copper and Risk of Cardiovascular Disease Mortality …
The role of serum copper as a putative risk factor for CVDs requires further exploration. The exact mechanisms underlying the association between elevated serum copper …
Serum copper, zinc and selenium levels in women with …
Objective: To compare the serum levels of copper (Cu), zinc (Zn), selenium (Se) and copper/zinc ratio in women with unexplained infertility and fertile women. Subjects and methods: This was a cross-sectional analytical study that compared 75 consenting women who had unexplained infertility with 74 fertile women that were controls. Both groups ...
Lighter serum copper isotopic composition in patients with …
The occurrence of non-alcoholic fatty liver disease (NAFLD) is globally increasing. To challenge the current incidence of NAFLD, non-invasive markers that could identify patients at risk or monitor disease progression are an important need. Copper intake and organ copper concentrations have earlier been linked to NAFLD progression, …
Not so Element-ary: A Copper Conundrum
Alternate biomarkers of copper, such as platelet copper, erythrocyte copper, and erythrocyte superoxide dismutase, have all been shown to be as unreliable as serum copper and are not routinely used in assessing copper deficiency [3,4]. The gold standard for the assessment of total body copper is liver biopsy with staining but its …
Association of serum copper (Cu) with
Published: 01 November 2023. Association of serum copper (Cu) with cardiovascular mortality and all-cause mortality in a general population: a prospective cohort study. …
Relationship of serum copper and zinc with kidney function …
While the exact mechanism underlying the serum copper-urinary ACR association is unclear, several potential mechanisms have been suggested by in-vitro experiments: (1) High level of copper may ...
The many "faces" of copper in medicine and treatment
Excess of copper is eliminated in feces, both as absorbed and unabsorbed metal ions and from biliary excretion, averaging 0.5–1.3 mg per day, and with small amounts in urine, saliva and perspiration. The average intake of copper by human adults varies from 0.6 to 1.6 mg per day and the main sources are seeds, grains, nuts and beans, shellfish ...